Phyto UltraComfort - 120 ct

Phyto UltraComfort

All Natural Pain Reliever Without Side Effects

*Certified Gluten Free by the Gluten-Free Certification Organization,

Phyto UltraComfort is a combination of ingredients designed to reduce minor occasional pain by supporting healthy enzyme and immune mediator activities.

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Patients who need relief from acute or chronic pain, have many pain medicines available to them. While most are effective, None Are Completely Safe—they all have significant side effects, including over-the-counter (OTC) medications.


  • Aspirin and ibuprofen (called NSAIDs or non-steroidal anti-inflammatory drugs) can damage the lining of the stomach. And because aspirin interferes with your blood's ability to clot, it can increase your risk of harmful bleeding.  Ibuprofen has been shown to cause chronic kidney disease and liver damage
  • Vioxx (rofecoxib), a prescription COX-2 selective NSAID, removed from the market after 5 years., was shown to increase the risk of heart attack, stroke, sudden death, and blood clots.
  • Celebrex (celecoxib) and Bextra (valdecoxib), the other prescription COX-2 selective NSAIDs, remain on the market despite the similarity of these drugs to Vioxx. The FDA warns that patients using these drugs longer than two weeks should be monitored closely by their physician.  Celebrex has been linked with kidney damage and Bextra has been linked with liver disease.

You do not have to risk dangerous side effects in order to achieve pain relief.  There are proven natural remedies you can use to control your pain without harmful effects to the body. 

As part of our pain management protocols, we use Phyto Ultra COMFORT.  This pain remedy contains several safe and effective medicinal plants and herbs, such as, white willow bark, boswellia serrata, turmeric and devil’s claw

White Willow Bark

Bark from the white willow tree is one of the oldest herbal remedies for pain and inflammation, dating back to ancient Egyptian, Roman, Greek, and Indian civilizations, as an analgesic (pain reliever) and antipyretic (fever reducing) agent.

The mechanism of action of white willow bark is similar to that of aspirin, Vioxx, Celebrex and Bextra, which is a nonselective inhibitor of COX-1 and COX-2, used to block inflammatory prostaglandins.

Various randomized, placebo-controlled studies comparing white willow bark with non-steroidal anti-inflammatory agents (NSAID’s) have shown the pain inhibiting actions to be comparable

Boswellia Serrata

The Boswellia species are trees located in India, Ethiopia, Somalia, and the Arabian Peninsula, and they produce a gum resin called olibanum, better known in the western world as frankincense. This resin possesses anti-inflammatory, anti-arthritic, and analgesic properties. Boswellia can inhibit the leukotriene biosynthesis in neutrophilic granulocytes by inhibiting 5-LOX, thus affecting various inflammatory diseases that are perpetuated by leukotrienes.  Clinically, the substance is used in the treatment of degenerative and inflammatory joint disorders.

A combination of Boswellia and curcumin showed superior efficacy and tolerability compared with NSAID’s for treating active joint pain.

Turmeric (curcumin)

Curcumin is a naturally occurring yellow pigment derived from turmeric (Curcuma longa), a flowering plant of the ginger family.  It has long been used in both Ayurvedic and Chinese medicines as an anti-inflammatory agent, a treatment for digestive disorders, and to enhance wound healing. Several clinical trials have demonstrated curcumin’s antioxidant, anti-inflammatory, and antineoplastic effects.

Curcumin has been proven to be more effective than celecoxib (Celebrex) in treating arthritis pain, for example. It has antioxidant, antiviral, and antifungal properties and it inhibits the function of molecules that play a role in inflammation because it contains high levels of natural pain-relieving COX-2 inhibitors. COX-2 is an enzyme responsible for the formation of prostanoids, (the fatty acids) which mediate inflammatory reactions that occur daily.  It’s also effective for local site inflammation from minor injury such as a scrape or cut, and post-surgical inflammation. It is non-toxic to humans, so it comes without the side effects of prescription medications.

Devil’s Claw

Native to southern Africa, and introduced to Europe in the early 1900s, this fruit gets its name from the tiny hooks that cover it.  Today, devil's claw is used widely in Germany and France to fight inflammation or relieve arthritis pain, headache, and low back pain. Animal and test tube studies suggest that devil's claw can help fight inflammation.

Devil’s Claw also has strong Cox-2 inhibiting power making it as effective for pain relief as prescription NSAID’s like, Diclofenac (Arthrotec), Celebrex, Mobic, Relafen.
Phyto UltraComfort* helps reduce occasional, minor pain by supporting healthy enzyme and immune mediator activities.


  • M. Z. Siddiqui*  Boswellia Serrata, A Potential Antiinflammatory Agent: An Overview, Indian J Pharm Sci. 2011 May-Jun; 73(3): 255–261.doi:  10.4103/0250-474X.93507
  • Baker RG, Hayden MS, Ghosh S. NF-κB, inflammation, and metabolic disease. Cell Metab. 2011;13(1):11-22.
  • Serhan CN, Chiang N, Van Dyke TE. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol. 2008;8(5):349-361.
  • Yeon KY, Kim SA, Kim YH, et al. Curcumin produces an antihyperalgesic effect via antagonism of TRPV1. J Dent Res. 2010;89(2):170-174.
  • Gayathri B, Manjula N, Vinaykumar KS, Lakshmi BS, Balakrishnan A. Pure compound from Boswellia serrata extract exhibits anti-inflammatory property in human PBMCs and mouse macrophages through inhibition of TNF-alpha, IL-1beta, NO and MAP kinases. Int Immunopharmacol. 2007;7(4):473-482.
  • Cuaz-Pérolin C, Billiet L, Baugé E, et al. Antiinflammatory and antiatherogenic effects of the NF-kappaB inhibitor acetyl-11-keto-beta-boswellic acid in LPS-challenged ApoE-/- mice. Arterioscler Thromb Vasc Biol. 2008;28(2):272-277.
  • Sengupta K, Alluri KV, Satish AR,et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-LOXIN for treatment of osteoarthritis of the knee. Arthritis Res Ther. 2008;10(4):R85.
  • Karimifar M, et al. (2017). Evaluation of the effect of Elaeagnus angustifolia alone and combined with Boswellia thurifera compared with ibuprofen in patients with knee osteoarthritis: a randomized double-blind controlled clinical trial. DOI:
  • Kim DS, Kim JY, Han Y. Curcuminoids in neurodegenerative diseases. Recent Pat CNS Drug Discov. 2012;7(3):184-204.
  • Aggarwal BB, Yuan W, Li S, Gupta SC. Curcumin-free tumeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of tumeric. Mol Nutr Food Res. 2013;57(9):1529-1542.
  • Funk JL, Frye JB, Oyarzo JN, et al. Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis. Arthritis Rheum. 2006;54(11):3452-3464.
  • Goel A, Kunnumakkara AB, Aggarwal BB. Curcumin as "Curecumin": from kitchen to clinic. Biochem Pharmacol. 2008;75(4):787-809.
  • Chrubasik JE, Roufogalis BD, Chrubasik S. Evidence of effectiveness of herbal anti-inflammatory drugs in the treatment of painful osteoarthritis and chronic low back pain. Phytother Res. 2007 Jul;21(7):675-83. Review.
  • Ernst E, Chrubasik S. Phyto-anti-inflammatories. A systematic review of randomized, placebo-controlled, double-blind trials. Rheum Dis Clin North Am. 2000;26(1):13-27.
  • Uehleke B, Muller J, Stange R, Kelber O, Melzer J. Willow bark extract STW 33-I in the long-term treatment of outpatients with rheumatic pain mainly osteoarthritis or back pain. Phytomedicine. 2013;20(11):980-4.
  • Abdelouahab N, Heard C. Effect of the major glycosides of Harpagophytum procumbens (Devil's Claw) on epidermal cyclooxygenase-2 (COX-2) in vitro. J Nat Prod. 2008 May;71(5):746-9.

  • Baghdikian B, Lanhers M, Fleurentin J, et al. An analytical study, anti-inflammatory and analgesic effects of Harpagophytum procumbens and Harpagophytum zeyheri. Planta Med. 1997;63:171-176.
  • Denner SS. A review of the efficacy and safety of devil's claw for pain associated with degenerative musculoskeletal diseases, rheumatoid, and osteoarthritis. Holist Nurs Pract. 2007;21(4):203-7.

Active Ingredients
White willow Bark, Boswellia Serrata, 5-Loxin (Boswellia serrata standardized to contain 30% 3-acetyl-11-keto-beta-boswellic acid), Turmeric extract (standardized to contain 95% curcuminoids), Devil’s Claw, DL-phenylalanine (fee-form)

Inactive Ingredients
Vegetarian capsule (cellulose, water), ascorbyl palmitate

*Certified Gluten Free by the Gluten-Free Certification Organization,

Suggested Use:

Mild to Moderate Pain:
Take 2 capsules 1 – 3 times daily.  If you have a sensitive stomach, take with food and 8 oz of water.

Severe Pain:
Take 2 capsules every hour for 4 hours or until pain level has decreased by 50%; then decrease to 2 capsules every 4 hours.

Phyto UltraComfort Alleviates Pain from the Following Conditions:

  • Peripheral Neuropathy
  • Headaches
  • Low Back Pain
  • OsteoArthritis Pain
  • Rheumatoid Arthritis Pain
  • Muscle Strains & Sprains
  • Fibromyalgia Pain

Note:  If you do not notice significant pain relief in 24-48 hrs, Add Protease IFC along with the Phyto UltraComfort.


  • This product contains salicylates. Do not take if allergic to aspirin. Do not combine with aspirin or other products containing salicylates.
  • Not to be used by pregnant or lactating women.
  • Not to be used by children (under 18).
  • Do not take with anticoagulant or antiplatelet drugs.
  • Do not take if you suffer from chronic stomach ulcers

Always consult your health professional before use.
PHENYLKETONURICS: CONTAINS PHENYLALANINE. Keep out of the reach of children.

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